Preparation of collagen burn-healing membranes
نویسندگان
چکیده
Collagen protein is obtained from fresh pigskin through hydrolysis with trypsin. By further adding extracts from scutellaria baicalensis (a Chinese herb), glutaraldehyde and etc., a novel type of collagen burn-healing membrane can be prepared. This novel type of membrane has a porous cross-linked netlike structure. The degree of crosslinking and mechanical properties of the membrane are examined; the optimal formulation and process parameters within preparation of the membrane are summarized. Based on the results from an in vitro test, the membrane enables its embedded medicines to possess a long-acting and slow-releasing property.
منابع مشابه
The Effect of Transplantation of Collagen Hydrogel with Adipose-Derived Mesenchymal Stem Cells on Burn Wound Healing in Rats
Background: Cell therapy is one of the most challenging methods in the healing of burn wounds in the world. The present study aimed to determine the effect of collagen hydrogel with adipose-derived mesenchymal stem cells on burn wound healing in an animal model. Materials and Methods: The present study was experimentally performed on 24 Wistar rats. Burn wounds were created on the skin of rats...
متن کاملAdvantages of Collagen Based Biological Dressings in the Management of Superficial and Superficial Partial Thickness Burns in Children
The ultimate goal in the management of burn wounds is to obtain physiological closure in the shortest period of time. Traditional burn wound management involves cleansing, debridement and provision of a moist environment to encourage the process of natural healing. Hence, an ideal dressing material has to maintain a moist environment, act as a bacterial barrier, and as a medium for free exchang...
متن کاملEffects of Minoxidil Gel on Burn Wound Healing in Rats
Background: Minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. These in-vitro effects proposed minoxidil to be a potential antifibrotic agent. The present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats. Materials and methods: Wis...
متن کاملEffects of Minoxidil Gel on Burn Wound Healing in Rats
Background: Minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. These in-vitro effects proposed minoxidil to be a potential antifibrotic agent. The present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats. Materials and methods: Wis...
متن کاملThe Healing Effect of Curcumin on Burn Wounds in Rat
BACKGROUND Burns are still considered one of the most devastating conditions in emergency medicine affecting both genders and all age groups in developed and developing countries, resulting into physical and psychological scars and cause chronic disabilities. This study was performed to determine the healing effect of curcumin on burn wounds in rat. METHODS Seventy female Sprague-Dawley 18...
متن کامل